I have a Cooler Master HAF-X case, and not to long ago I replaced a Cooler Master Hyper 212+ with a Corsair Hydro Series H100I. the reason was because the Hyper 212 interfered with dimm slots, So I put the radiator up top under my 2 x 200mm fans with 2 120mm providing a "push". If you have a tower that can support a radiator such as this or even a H80 the I would defiantly do it. I have great cooling even under heavy loads.